Lung cancer is the leading cause Fabric Softener of cancer-related death worldwide.Aberrant splicing has been implicated in lung tumorigenesis.However, the functional links between splicing regulation and lung cancer are not well understood.Here we identify the RNA-binding protein QKI as a key regulator of alternative splicing in lung cancer.We sho
We report here on experimental and theoretical efforts to determine how best to combine drugs that inhibit HER2 and AKT in HER2(+) breast cancers.We accomplished this by measuring cellular and molecular responses to lapatinib and the AKT inhibitors (AKTi) GSK690693 and GSK2141795 in a panel of 22 HER2(+) breast cancer cell lines carrying wild type
We introduce the waveform capture device (WCD), a flexible measurement system capable of recording complex digital signals on trillionth-of-a-second (ps) time scales.The WCD is implemented via modular code on an off-the-shelf field-programmable gate-array (FPGA, Intel/Altera Cyclone V), and incorporates both time-to-digital converter (TDC) and Audi
Abstract Background In many countries Foot Peel worldwide orphan drug regulations are installed but only the United States of America and Japan have an orphan device regulation.For many years surgeons have used off-label or self-assembled medical devices for the prevention, diagnosis or treatment of rare disorders.Four examples are given: an extern